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NITROSODIPHENYLAMINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AGAINST OXIDATIVE STRESS PATHOLOGIES


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pg_0032
The Patent Office Journal 11/08/2006 14556
(12) PATENT APPLICATION PUBLICATION
(19) INDIA
(21) Application No.: 01461/KOLNP/2004
A
(22) Date of filing of Application: 04/10/2004
(43) Publication Date: 11/08/2006
(54) Title of the invention:
NITROSODIPHENYLAMINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
AGAINST OXIDATIVE STRESS PATHOLOGIES
(51) International classification
: A61P 39/06; C07C
237/40; C07C
243/06; C07D
213/75; C07D
213/76
(31) Priority Document No
:
02/03025
(32) Priority Date
:
11/03/2002
(33) Name of priority country
:
FRANCE
(86) International Application No and
Filing Date
:
:
PCT/EP03/01370
12/02/2003
(87) International Publication No
:
WO 03/076406
(61) Patent of addition to Application No : NA
Filed on
: NA
(62) Divisional to Application No
: NA
Filed on
: NA
(71) Name of Applicant:
MERCK PATENT GMBH
Address of the Applicant:
FRANKFURTER STRASSE 250, 64293 DARMSTADT,
GERMANY
(72) Name of the Inventor:
LARDY, CLAUDE; FESTAL, DIDIER;
CAPUTO, LIDIA; GUERRIER, DANIEL
Filed U/S 5(2) before The Patents (Amendment)
Act, 2005: YES
(57) Abstract:
Compounds of formula (I) in which each of the phenyl rings
represented is optionally substituted one or more times; n represents
an integer selected from 0, 1, 2, 3, 4 and 5; W represents -CO-or -
SO
2
-; Z represents H; alkyl; aryl; or arylalkyl; R
1
represents any
monovalent organic group; and the pharmaceutically acceptable salts
thereof, can be used in the treatment of pathologies that are
characterized by an oxidative stress condition.
(FIG. 1)

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